Neprinol - Powerful Systemic, Proteolytic, Blood Cleansing Enzymes
Neprinol - Powerful Systemic, Proteolytic, Blood Cleansing Enzymes

Neprinol - Powerful Systemic, Proteolytic, Blood Cleansing Enzymes

Regular price $89.00 Sale

Product Information

Neprinol is a blend of all-natural systemic enzymes. Systemic enzymes support healthy levels of fibrin and other debris in the blood. Cleansing the blood of debris can support healthy cardiovascular and liver function as well as maintain a healthy inflammatory response to everyday activity.

Neprinol's microbial and plant-based enzyme blend tested to be more than 500 percent stronger in fibrinolytic activity than the leading animal-based enzyme formulation, based on third party fibrinolytic testing. It’s both effective and vegan-friendly.

How Neprinol Works

The blend of all-natural systemic enzymes in Neprinol break down debris in the blood, such as excess fibrin and other unwanted proteins. Breaking down these components supports normal inflammatory levels in response to stress and restores the blood to its naturally pure state. Systemic enzymes are similar to digestive enzymes. The only difference is systemic enzymes primarily target the bloodstream, instead of the gastrointestinal tract.

Advanced Fibrin Defense

Fibrin is a major component of scar tissue and blood clotting. Healthy adults maintain a normal fibrin equilibrium, which prevents the blood from becoming too thick and sticky. However, aging bodies have a more difficult time maintaining proper blood viscosity.

Neprinol contains a blend of fibrinolytic enzymes that support healthy blood viscosity. When healthy, our bodies will normally secrete sufficient levels of plasmin, an enzyme that acts as a natural blood thinner. Plasmin is responsible for maintaining normal blood viscosity by removing unnecessary proteins, specifically fibrin. Neprinol—like many fibrinolytic enzymes—supports healthy fibrin levels.

Blood Viscosity and Neprinol

Whole blood viscosity is a measure of the blood’s ability to flow freely throughout the arteries and veins in the circulatory system. It’s also described as the thickness and stickiness of blood. Having high blood viscosity increases the resistance of normal blood flow, which causes friction and abrasion against the vessel walls. It can also lead to decreased oxygen delivery to organs and tissue inflammation.

In a recent clinical study, Neprinol had a significant impact on normalizing whole blood viscosity, thereby reducing the thickness and stickiness of blood.

Effective Immune System Support

The immune system is the body's biological system that protects itself from disease. One of the ways the immune system protects the body is by producing antibodies in response to antigens. Antigens are anything in the body that’s capable of inducing an immune response. This includes bacteria, viruses, and even pollen. Antibodies are able to deactivate antigens, but when doing so, they create proteins in the bloodstream.

The superior enzymatic potency of Neprinol can help eliminate these proteins, supporting the body’s natural repair processes as well as limiting inflammation from overexertion.

Efficacy is of the utmost importance to doctor and patient alike. Neprinol addresses this concern with a proven potency that can be administered by healthcare professionals. Neprinol can be recommended for both clinical use and therapeutic applications.

Wave a pain-free goodbye to joint discomfort and poor circulation with Neprinol.

Neprinol Benefits include:

  • Reduction in inflammation
  • Blood cleansing
  • Removes circulating immune complexes
  • Dissolves arterial plaque
  • Reduces the risk of clots by dissolving fibrin in the blood
  • Eliminates the risk of DVT (deep vein thrombosis)
  • Strengthens the immune system
  • Kills bacteria and viruses
  • Improves circulation
  • Speeds the recovery from strains, sprains, fractures, bruises and surgery
  • Dissolves scar tissue
  • Keeps gums healthy by reducing dental plaque
  • Protects the cardiovascular system



Product Reviews

Excellent! High quality enzymes!

Neprinol is my #1 choice for many reasons: bone and joint health, immune system health, heart and vascular health. Both my husband and I have noticed remarkable changes in our health. Both of us have arthritis in our joints and knees. Before taking Neprinol, we were having a lot of pain especially in our knees. We have been taking Neprinol for a several months and essentially pain free in our knees! I also can feel a big difference in cardio health. Before Neprinol, I was taking aspirin daily for my heart per doctor’s orders. However, when I found Neprinol and shared the info with my doctor, he approved my taking Neprinol and stop the aspirin which has been a true blessing. I have also seen a big difference in my immune health - have not had a cold in over 2 years, have even avoided getting COVID! These enzymes work in remarkable ways and highly recommend.

Scar tissue buster

I was making regular ER visits (4X a year) for bowel obstructions due to adhesions. I also had so much scar tissue in my rectum from colon surgery. I was desperate and looked for solutions online. One site mentioned Neprinol for scar tissue. I started taking 9 capsules per day, as recommended for therapeutic effect, in September2016. In December 2018 I had a surgical procedure and all of the scar tissue was gone from my rectum. My colorectal surgeon was surprised and very impressed. I can’t speak to heart benefits but I have proof that it worked in removing my scar tissue. I have only had one intestinal blockage since August 2016, in Jan 2020. The reason was from not taking the Neprinol for 5 months. For me that is further proof that the Neprinol was what cleared my scar tissue. I was down to a maintenance dose of 3 capsules a day before I stopped completely. I went back to 9 capsules a day after my hospitalization. I won’t ever stop taking it again.

Favorite product

My favourite health supplement. Really quality product that assists greatly with reducing inflammation issues in the body. So many benefits and feel so much better taking it.

Amazing product!

I was told I needed to have a colon removal due to a stricture that was dangerously narrow due to years of inflammation from ulcerative colitis. I began a protocol to heal my gut naturally and used this 2 x 3 capsules a day for about 6 months. The doctors were shocked when my scar tissue in my stricture had improved enough to complete the colonoscopy and showed no signs of active U.C. I continue to take 3 capsules a day and am grateful. was able to avoid life changing surgery.

So happy

I can't hype this product enough, carpel tunnel syndrome gone! hubby's itchy eyes gone! better sleep, better bowel movements, no aches and pains, no headache! wow! Highly recommended 


This was the finest buy I've ever made after receiving a recommendation from a health care provider. These vitamins have significantly improved my body's inflammation and circulation. I used to wake up with numbness and discomfort all night long. After barely a week of doing this, it is entirely gone.

Breathing helped

My breathing issues disappeared, thanks to Neprinol.


I bought Neprinol for my scar tissue, pain, and frozen shoulder after an injury to my shoulder. It's been 10 months since I got injured. The healing is very slow. I have only taken Neprinol for two weeks but I can feel the difference. Something started to shift. I knew previously that this product was working because I used to get it for my mom. She had a cardiovascular problem and it did wonders for her. After she passed away the doctors said she was taken care of very well.


My mum 82 years old has been taking this product since long ago. She is still as healthy as ever. Her blood vessels are all beautiful, circulation are prefect. Memory super.

So far, so good

I have only been taking a therapeutic dose of Neprinol for 12 days but so far, so good. I noticed I can do a short morning run with more ease than before. No side effects have been observed from taking 9 pills a day which leads me to assume the quality of the product is good and not harmful. I will continue with my current dosage for several weeks longer before doing a test for arterial plaque to see if it's gone or reduced. It's too early to tell for sure but the osteoarthritis in my hands could be improving. Watch this space!


Excellent support for circulation. Stops chest pain and makes easier to breathe for pulmonary hypertension. Reduced glaucoma high eye pressure. Helps dissolve blood clots and reduces their return. These are all family experiences. We use this instead of aspirin for healthy circulation.

Can't be happier!

Had an artery CT scan and no sign of plaque (my cholesterol has been between 7-11 for years and I am 59) and I believe it’s because of Neprinol keeping the fibrin at bay and my blood at a good viscosity level. Can’t be happier with this product😀

Great product for circulation

My stepdaughter told me about Neprinol as she takes it for relief from Fibromyalgia after telling her about my sudden Pruritus which attacks during the night and robs me of a good night’s sleep. Though I’d seen a doctor who prescribed me something that made me lethargic and reluctant to take. Since I started using Neprinol, I’ve never experienced it again and it’s been almost 1-1/2 years. Great product fro circulation.


The quality of Neprinol is great. Ingredients clean and effective, trust-full brand Also their probiotics are great.the benefits i notice are mucus dissolution in my case I took it for cysts to early to tell You have to take at least 3 months.I see increased immunity feel less bloated also.

No more cyst

I had surgery for a breat abcess a while ago and it left a little cyst that the doc wanted to remove. I started taking this along whit daily massages after bath and the cyst dissapear


Neprinol is excellent for dissolving lumps and cysts, and overall well-being. Have recommended this product to several people and they all experienced great results.


I can’t speak highly enough of this product. It helps in so many ways- so many benefits to physical and digestive health. It removes so much inflammation from the body.


I have breast cysts, i use this product to eliminate these cysts, i use the Neprinol since 1 month just, but i already feel the benefits, my breasts doesn't hurt that much, like before... The ingredients of the product is excellent.

 Dogs health

I saw an improvement in my dogs coat and energy and agility levels after using this product. The ingredients are of course great because Arthur Andrew is a trusted company.

Guizhu C.

I love this product. It helped a lot with my joint pain

Debbie S.

Great product!

Connie H.

I've been taking neprinol for about six months. When I ran out and didn't reorder, I started noticing a difference in how my digestion works. I believe it's beneficial to me to take it and I'll continue to do so. -Connie

Gloria C.

I have been using Neprinol AFD for years and believe I am getting good results healthwise.

Chul L.

Hello, One of my client, since she has been take a pills for a couple years, she is happy with this pills, her symptoms has been much improved. she will continue to take this pills. Last shipment was very terrible, it takes to here more than two weeks, exactly 17 days to here with appearance of package was so dirty and contents was wet. Best regards, Lee

Cathi-li G.

I started using Neprinol AFD around October 2015 for a nagging knee problem I began experiencing in late 2014. Despite using doctor prescribed steriods and other medications for a few months none of them had any positive effect for me. Neprinol AFD was recommended to me by my natropath and I'm happy to say that there has been noticeable improvement thus far.

Jonathan B.

We love this supplement. We order it, we take it, we feel better, we order more. I made the mistake of trying to live without it when we ran out and we paid the price. We started getting sick with the flu, colds, everything everyone else was getting. I am placing another order today so we don't run out.

Clinton K.

Great for eliminating bothersome inflammation in the joints and muscle. Not to mention no more heartburn. I'm a strong believer in it.

Virginia T.

I am so grateful a product exist that does what this product does. Everything you need for healthy arteries, fibrin control And enzymes for functions in the body are available.


After reading all the reviews on Neprinol I have to order it and theSerretia. I had a stroke in 2009 and the warfarin and Statin drugs they put me on had me in constant pain and almost crippled. When I was in the hospital I felt great, couple of weeks later the pain in my body was crippling and I was using a walker and cane to get around. I quit taking the Statin and eventually felt much better. Now I have stopped taking all the warfarin cut back to half dose and taking nattokinase and a baby aspirin daily. Started to see results immediately. Now I am ordering Neprinol with added Seretia. I would recommend it to anyone for sure

Ying-ju l.

Good support for health maintenance.

Carol B.

I am not stiff anymore. I use it along with Serrapeptase. Feeling younger!

William B.

I took the 4 tablets 3 times daily for an entire bottle, about a month, and have yet to notice a change in the aches and pains of my body.

Connie H.

I started taking Neprinol last summer to assist in healing my gastrointestinal tract, along with boosting my immune responses. (I was diagnosed with colitis, and have celiac disease.)I have been so unwell for so long, I had almost given up on feeling normal. I'm happy to say that the healing is taking place and I feel better than I have in years. Neprinol is only part of my supplement regimen, but I believe it has contributed a much needed help to my body.

Jerry W.

It's great and helping to make my grandpa better.

Yong S.

I have been taking Neprinol AFD and Syntol AMD for about a month. I have been satisfied with their overall quality. Best wishes for your success.

John D.

After discovering the inherent value of enzymes, my wife and I began using Neprinol several years ago. We found Arthur Andrew Medical via the internet and found them to be professional in their attitude, advertising, and product information. Our attention was drawn to Neprinol because of the unique enzyme(s) combination, as we were looking for a natural product to address joint pain. Eight years ago my wife had surgery to her shoulder in order to repair a torn rotator cuff. She still had lingering pain and discomfort in that shoulder years after the surgery. Choosing to use Neprinol instead of pharmaceuticals to manage the joint pain we gave Neprinol a try, and to our surprise it worked. It completely alleviated her discomfort and allowed her to go longer periods of time in between dosage. We believe this is a very wonderful product. Best Regards, John & Mary Ann Desport Kamiah, Idaho

Edward H.

Arthur Andrew Medical has a great product, Neprinol AFD. I have read about the research athat went behind the product's formulation, the fact that the capules are phthalate free Acid Armor with enteric properties,the Advanced Fibrin protection, and that Neprinol AFD helps clear the blood and supports proper joint and immune fun

Marissa B.

I enjoyed the products; however, is there a way to get therapeutic results without having to take so many a day?

Marge S.

Taking Neprinol is part of my daily regimen. It has controlled the chronic pain in my lower back. Thank you

Geanine H.

I have confidence in Arthur Andrew product and customer satisfaction. I first heard of this company thru the Magnesium Advocacy Group. This group consists of highly experiences and educated health studies persons. I have recently ordered several other products after reading detailed information from Arthur Andrew. I thank you for you efforts to continue quality and service.

Freya S.

I love the benefits neprinol has given me. It helps with my digestion greatly-went off for a few weeks and really suffered w/out it. Digestion as well as joint swelling and pain returned.... Went back on the neprinol and I'm feeling way better!

Isaac E.

over all this is a great product. I've been using it for over a year now and nothing out there compares to the efficacy of this product. This product has help me a whole lot.

Zheng L.

My friend suggests me that this medicine is very useful.I buy 4 bottles and give it to my friends .I hope I can get the medicine faster at the next time.thanks!

Nora B.

Neprinol AFD seems to be helping with the stiffness that cold weather brings on. I'm still on my first bottle but plan to re-order and keep subduing inflammation.

Jillorna U.

I have been on Neprinol for several years and my circulatory system as progressively improved with this wonderful supplement!

Cecilia D.

Arthur Andrew Medical has great products that really work. I will continue ordering from them, I love the quick shipping also.

Dennis H.

Some positive results

Connie H.

after taking approximately 6 capsules a day, three in the a.m., and three before going to bed, I've noticed an increased strength and function with my knees. there is less pain, and more strength as I take my walks. I believe it is the neprinol that is helping me.

Sheri-ann E.

Neprinol was recommended to me to hopefully assist with an issue with my knee. Unfortunately one year has passed and despite many visits to the doctor and tests, no definitive diagnosis has been forthcoming. The best way I can describe the issue, is that it feels that my knee is being constricted by several bands to the point of feeling like circulation maybe cut off. I am also unable to full straighten out my leg as a result. I have been taking the Neprinol about one month now (2 tablets a day) and so far there has been a reduction in the tightness / constriction feeling behind my knee. This is a positive sign as many other suggested changes to diets and other medications have not produce any noticeable changes. Hopefully over the next 3 months the improvements will be even more evident.

Erika M.

Ive read that Serretia worked better with it and it's true. Will keep buying.

Gina R.

I had added this Arthur Andrews product to my normal routine to see if it had any added benefits. Didn't seem to make any significant changes, so I'm going to continue with the Digestive ADS and the Syntol for treatment of my RA symptoms.

Jusette D.

helped with my joint pain.

Richard G.

I purchased this to help with my yeast problem,i have nocticed some change since taking it.

Jason R.

Have been taking the product for about 3 months now and my joint pain has decreased tremendously. Will continue to use.

Joanna L.

Hi, generally speaking I feel good. I am taking Neprinol AFD and Fibrovera AHS just as a prevention. I believe it is rally good booster for my body. Thanks,J.

Carol B.

I believe in this product, that it is doing the job it is supposed to. I will continue to use it and regain my health.

Donald C.

My exercise recovery time and flexibility and much better since I started to take Neprinol

Hugo M.

I like taking Neprinol because it gives me a feeling of physical well being and confidence. I get a feeling of vitality and I like that.

Millie B.

Neprinol is a great product that has worked for me. I'm a true believer in this company and this product!

Ingrid J.

My husband has a tendency to have a high blood pressure. We received some recommendation to take Aspirine, but i believe this is a better way to ensure good good blood circulation. And indeed it seems it is working as he now seldomly has a high blood pressure. Believe it might also provide a good protection against cancer. He has a hernia spatiale and this could eventuelly turn into cancer...

Wells C.

only taking for a short time its hard to say how it may have helped me except bring my blood pressure into a normal range.

Joyce S.

After using Neptinol for several years I must admit not always following the instructing consistently my arteries have become unblocked

Isaac E.

Great product, very efficient and one if not the only most effective systemic enzymes out there.

Millie B.

I'm always surprised by how fast I receive my orders from Arthur Andrews! I have sometimes received orders in as little as 3 days. Please keep up the good work. I wish all companies operated like you do!

Margaret B.

I purchase Neprinol AFD because I wanted to reduce scar tissue in my body. I have a scar from an old surgery, as well as possible liver scarring, as in cirrhosis. I am hoping that this product will help my body to break down cellular debris throughout. It seems to be helping, I am taking vit c internally and using vit E topically on the scar itself, also. My skin is getting softer on the scar itself, and there is less pulling on the surrounding skin. I will know better after using this for a few more months.

Homer P.

I am very much into supplementing, because I am single and not a cook. I enjoy good health by taking good products.I have friends & family that seek my advice on supplements.

Jonathan B.

We love this supplement. Feeling so much better overall. More energy every day.

Susan S.


Aimee Z.

Definitely recommend this product and company. High quality, fast shipment!

Frank I.

I was trully amazed with the unexpected results after my first experience of taking Neprinol. Neprinol has eliminated pain caused by inflamation in my knees, has benfitted my digestion to a degree that has allowed me to eat foods that at one time I would not dare to eat, I no longer depend on antiacids. I keep it on hand all of the time , and I recommend Neprinol to everyone who talks to me about joint or muscle pains or digestive issues.

Kala B.

works great

Isaac E.

top notch product ; great purchase very effective

Nikolas R.

I have been dealing with a scar tissue issue and was seeking a safe way to decrease scar tissue in areas which can't be massaged. Neprinol AFD decreased scar tissue and allowed for more flexibility.

Kala B.

in just few days feel big difference in good way

Hollie P.

This is a really good product. My ESR and CRP levels were very high and I had a lot of inflammation. I've been taking Neprinol, Serretia and Syntol and my most recent blood work came back in the low normal range. My doctor was amazed by the results and told me to keep doing what I was doing.

Jillorna U.

Thank you for this amazing product!!

Elisabeth V.

Really helped rid the bod of fibrin, calmed the nerves, helps other botanicals do their jobs, and you will never look at your poo the same again.

Stephanie S.

I really noticed its potency when I stopped using Neprinol. Healing took much longer and was not as comprehensive. If you are a light worker, you will really appreciate the power of this product to speed your results.

Susan S.


Ying-ju l.

Steady improve my health and reduce my symptom. Good health supplement. Thanks!

Thomas R.

Seems promising but the jury is still out, will continue

Millie B.

I'm so pleased with the results of Neprinol. I've been using for several years and am glad that this product actually does what the ads claim about it. Also the service from Arthur Andrew is quick and very efficient. I highly recommend this company and this product!

Michael B.

I bought Neprinol for it's blood cleansing properties hoping to increase blood circulation by clearing arteries and blood vessels of plaque buildup. I am halfway thru my therapeutic cleanse and have noticed my stamina is better. I take that as a good sign things are getting better.

Isaac E.

Best systemic enzymes out there the efficacy of it awesome

Freya S.

I really enjoy the benefits of neprinol. My dr perscibed high doses for endometriosis and after a yr I have weaned my doses down and am pain free!!

Norman P.

I believe in this product. I have been taking neprinol for several years and can attest to its usefulness. My health is good . rarely have sicknesses,and I generally feel good .


Sorry for my poor english. Why does Neprinol smell so bad? In about two months, the smell is increasing in a unpleasent odor. Why does it happen?

Larry C.

I was diagnosed with Hypersensitivity Pneumonitis caused by Bird dander which as lead to Pulmonary fibosis. Your product as been claimed to be able over a period of time to heal scar tissue both surface and internal and that is what pulmonary fibrosis is. I had taked your product for 38 days and I have not experienced any change at all in my blood oxygen levels taken with a oxymeter. It may be a good product but not in my situation. Not what you wanted to hear but it's the true.

Martin B.

I've been using this product as a substitute for cholesterol drugs (lipitor) and to reduce chest/heart pains. It seems to work well. I would recommend it highly

Barbara H.

I had some heart issues that scared me into the emergency twice. Although I had tests and a procedure done, ultimately I did not receive the care from my doctor I expected possibly because I refused to take statin drugs (I had side effects). While I received "good news" after the procedure, my problem remained. So a friend of mine and I went on the internet to search for something that might help. That is how I found Neprinol. My heart issue has not come back since I have been taking Neprinol, and it is very comforting to me. That is why I am a returning customer.

Ellen K.

I've been using Syntol for a bit over 4 months. Initially I believe I experienced some die off symptoms (fluish, rash on eyelids) but after a couple weeks I began to feel better than I had in years. I continue to use on a maintenance basis.

V. Page

My wife had a blood clot in her leg. within six months at max dosage her blood cot was gone. Confirmed by hospital and her vein doctor. They were going to put her on Coumadin and we challenged a medical doctor. Our annual lab test were excellent on all stats. My doctor copied your research info on his computer. we both us neprinol and vitamins only no prescriptions. I also take Neprinol daily.

Lisa J.

I've been taking Neprinol for over a year now- and I would continue with this product for life even if I wasn't taking it for a specific problem. I feel like I am an overall healthier person for taking it. But - though Arthur Andrew doesn't promote it for pulmonary issues - I have scar tissue in my lung area and Neprinol allows me to live a normal life. The few times I haven't taken it (once I was having a procedure and Neprinol is a blood thinner and a couple of times I didn't coordinate it well with my meals and decided to skip it), I woke up gasping for air. I truly believe I would be in and out of hospitals and treatment without Neprinol. If you have breathing issues, I'd give it a try.

Gerald G.

Excellent product

Susan S.

great product Neprinol

Elizabeth M.

Excellent product. Best relief for joint pain I have used in years. My energy level is way up too!

Jo A.

Great product

Cecilia D.

Superb Products!

Barbara H.

I used to have occasional heavy and irreagular heart beat, but since I have been taking Neprinol, my problem has not returned. It really works for me.

Diana G.

Have been using this product for quite some time, I feel the whole line has been beneficial to my overall health! LOVE!!!

Gretchen T.

A friend was experiencing symptoms of Trans Ischemic Attacks (TIAs,) aka: mini strokes; while searching for natural interventions for him, I found Arthur Andrew Medical on the web. Originally, my friend was using the Raw Nattokinase formula, until it was no longer available. Substituting the Neprinol AFD was an upgrade to truly advanced fibrin defense. My friend went from having frequent mini-stroke symptoms, and scared as hell, to being pretty much symptom-free. When I started having the same symptoms, I knew what was happening, and started using Neprinol AFD. The symptoms of TIA virtually stopped while taking this product every day. I switched to, and continue to use, FibroVera AHS, realizing remarkable benefit from the additional hormonal support. Based on my own experiences, I highly recommend both these products as safe alternatives to dangerous prescription drugs, that deliver real life-changing results.

Rick T.

This a great product with some serious research behind by the looks of the list of ingredients. And mentioning the ingredients you could not get them separately for this price!

Tucker G.

Blood pressure problems remain unchanged after 30 days. Not even a 1% improvement. I think I should stay with Nattokinase

Nabil K.

This is a great product and we take it with Serretia. It appears to work. I also like the customer service.

Virginia T.

Florphage makes intestines feel more settled

William S.

I am very pleased and it has greatly decreased my back problems

Freya S.

Great product. Not sure that my well being would be so good w/out it!!!

Jennifer P.


Nancy K.

i have been taking Neprinol AFD for 2 months. I feel that I have more energy and feel more alert. I had previously taken Neprinol and then stopped for about a month and then stated taking Neprinol again. I could feel a bodily difference and I am glad that I am taking Neprinol AFD again. I love this supplement.

Geoff S.

I have only been taking the Neprinol for a few weeks but have already noticed an improvement.

B R.

My 14 year old son has bee on this product for 4 years, it has kept his blood perfectly clean and free flowing. Thank You!

Cherling A.

Neprinol does work to cleanse my blood. Fantastic!

Rick T.

I think this is a great product and when combined with serretia its even better. I take the recomended dose of neprinol and add one one serretia its even more effective for me. I wont go with out it.

Jack M.

My significant other takes these supplements and feels a whole lot better. He has been taking them for approx. 10 months and will continue.

Cecilia D.

I will continue purchasing Neprinol AFD from Arthur Andrew Medical. Neprinol really works. Great and fast service!

Ying-ju l.

Very Good service and product

Constance T.

My Osteopath says he can tell it has helped my arm I seriously strained recently, and I can feel it has helped a great deal. My husband, a fine cabinet maker who has to be on his feet a lot, is now taking it and says his feet even feel better. A co-worker I told about it is very satisfied with the results for his joint pain. I want to try your other formulas soon .

Manuel s.

I never received it

Freya S.

This product is really great. It has been helping w/inflammation and gut symptoms! Can't say enough good things about it. I will continue to use for sure!

Mark W.

Overall I'm happy with the Neprinol product. Sometimes enzyme supplements are hard to judge in terms of effectiveness, etc. But after a few weeks of using the product some of the nagging symptoms I had (pain, stiff joints) have lessened a good deal.

Rick T.

This stuff works great! Seriously you cant find a product like it anywhere.

Skip P.

When taking this consistently I very rarely am super sore from my intense workouts. I feel like it helps keep inflammation at bay.

Nancy K.

Secon time trying Neprinol. I noticed a difference of having more energy and feeling just generally better. Was not sure the first time I ordered the supplement if this was the reason why I was feeling more energetic so I took a break from this supplement. I recently ordered Neprinol again and Now I know that Neprinol AFD is the reason for my feeling of more energy and wellbeing. Thank you for making a good quality product that does what it says it does

Michael W.

I continue to use this great product. I think it is working well and I will continue to use. Thank you

Clinton K.

Before taking Neprinol I had occasional aches and pains upon waking and getting up for no apparent reason besides just getting older. After buying and taking about a week they started subsiding little by little. By the end of a month I couldn't notice them anymore. That was 2.5 years ago and still take 3-4 a day in the morning and now at 63 feel great in the morning. If I run out and don't replace the bottle within 2-3 weeks the aches slowly start creeping back. When I get my new bottle and resume taking it they go away. I'm a believer.

Cecilia D.

This is a great product!!

Robert O.

Wonderful product.

Rick T.

this product works as advertised, it is helping me with my circulation and I can tell if I run out. No other product comes close to the types of ingtredients and quantity of ingredients as Neprinol

Susan S.

Become pain free what a great product Neprinol

Eduardo S.

I bought this based on the information I found in a health magazine. The logic behind the enzyme action within the blood stream seemed to make sense to me. It is my hope that within the next 2 months, I'll notice a increase in my energy and/or stamina. At this point I've noticed no ill effects taking the product 4 times a day.

michael H.

I had spine surgery in January 2012 which created epidural Fibrosis, various MRi's have shown a significant amount of scar tissue which there is no standard medical cure for. This lead me to look for alternatives. I also have high cholesterol and medium blood pressure. I first started taking 3 tablets twice a day but after 2 weeks felt very weak and tired, I carried on through but it was effecting my day. I noted that this is a side effect of detoxing. I have now reduced to 2 tablets twice a day and find I can manage this with no ill effects. It has been two month since starting regular use, so far to early to report any findings, but I am due for a blood test at the end of October 2014 and will report back on my levels. Sadly I wont be able to report back on my scar tissue through medical notes as no doctor will perform another mri just because I am taking Neprinol.

Dennis H.

Been taking for over a year and a half still have not seen the results I have been waiting for

Changle L.

Pretty fast distribution. Prett good effect

Freya S.

I have been taking high doses of neprinol for endo. My general overall health has greatly improved! I have less pain and better digestion

Susan S.

Love Neprinol really keeps me going!

Junyulie F.

I really cannot say the definite things, but I hope it's working, and want to believe it's working.

Cecilia D.

Neprinol AFD is a wonderful supplement. I have been taking Neprinol for a while now and will contiue to use it. It has made a difference in my health.

Susan S.

Love the service Arthur Andrew has and I love Neprinol I don't think I would be able to get out of bed and walk without it right now. Great Product.

Raymon H.


Dennis H.

I have peyronies disease been taking neprinol for 2yrs this February still have not seen any results yet

Lashaun R.


Helena F.

I took this for my hardening blood vessels and have good results after one month. I have been taking 2 in the morning and 2 in the afternoon.

Cathy B.

I feel so much better.

Kia T.

Very good product.

Susan K.

Unfortunately, I found that I was allergic to neprinol.

Cecilia D.

Great product, great service! I will continue ordering Neprinol AFD from Arthur Andrew Medical.

Diana G.

I use to take a well known brand for inflammation. I had to be careful with it because I would have reactions if I took too much. Neprinol is excellent. My body has responded well with no side effects whatsoever. I feel great!

Kate M.

I was taking this for about one month for neck pain and inflammation. it didn't really seem to make any difference but after reading all the 5 star reviews, I'll give it another go..

Terry H.

Too early to tell, but symptons appear improving.


I have been using Neprinol since early 2000.

Gregg H.

I bought this to help with inflammation and to help cleanse the blood. So far it seems to be doing a great job!

Angel A.

Love it seems to help with the side effects

Marie P.

No change in symptoms

Lisa J.

This is my second review for Neprinol. The first was for the incredible customer service I had received - but I didn't really know if the product was working. I used it for scarring on my lungs. I took six Neprinol after a surgery and continued for a few months and then decided to cut back to a maintenance dose, for general health as I liked the idea of supplementing my systemic enzymes as I age. However, after a month or so, I could tell my breathing was getting worse. Once I made the connection that the only change had been in cutting the Neprinol, I increased it to the maximum for 2 weeks (9 a day) until I could get through my dance class again, and am now back at 6 a day. It proved to me that this is a powerful product, and I am very grateful it exists. Otherwise, I would probably have to continue to have procedures on my lungs that was cause even more scar tissue to develop.

Freya S.

My dr has me on a high dose of neprinol for endometriosis. So far I am feeling good. It has also helped w/occasional "tummy troubles"


I surf the ocean around Maui and needed something for my knee. I was suffering from pain after a soccer injury to the cartilage. limited range of motion and the small obstruction was gone after taking Neprinol.

Cecilia D.

Neprinol AFD is a great product and I will continue to purchase it! I purchased it for inflammation and have felt the difference. Thank you!

Norman P.

it results in an overall well being on a daily basis.I rarely ever have a sickness of any kind. it is indispensible for me.


Doctor recommended Neprinol supports:

  • Normal immune function
  • Normal blood clotting
  • Normal antigen response
  • Fibrinolytic activity
  • Normal blood pressure
  • C-Reactive Protein reduction


Fibrin is a protein formed in the human body that is responsible for scar tissue and thrombus formation. Neprinol contains a blend of fibrinolytic (fibrin degrading) enzymes that specifically address fibrin levels in the body. When healthy our bodys will normally secrete sufficient levels of plasmin, our own natural blood thinner, which is responsible for maintaing normal blood solvency, by removing unnecessary accumulated protein. The normal process of removing excess protein can be enhancing by introducing fibrinolytic enzymes like those in Neprinol. Serrapeptase an exceptional finbrinolytic enzyme has been clinically shown to have the ability to break down large amounts of fibrotic scar tissue. This dissolved tissue over time may accumulate in the blood increasing viscosity and free radicals. The enzyme Nattokinase has been included in Neprinol because it has been shown to be similar to our bodys own plasmin, assisting to normalize blood viscosity by dissolving these lysed tissue cells. Neprinol is an excellent choice for anyone suffering from the damaging effects of excess fibrin.

Neprinol can be used for the following conditions:

  • Angina
  • Anti-inflammatory, Anti-edemic
  • Arthritis
  • Endometriosis
  • Fibrocystic Breast disease
  • Uterine fibroids
  • Fibromyalgia
  • High blood pressure
  • High cholesterol
  • Sinusitis
  • Peyronies
  • Peripheral Neuropathy (numbness)
  • Phlebitis / Thrombo-phlebitis
  • Sports and other injuries

and much more ……………

By supplementing and replenishing our bodys own natural enzyme stores, Neprinol AFD provides one of our most basic and essential biochemical needs. Neprinol AFD has been used to strengthen the immune system, maintain proper blood circulation and to support the bodys natural recovery mechanisms following physical stress due to sports and other strenuous work activities. It supplements the bodys own natural fibrinolytic enzyme levels, thereby helping to maintain normal fibrin, an underlying causative agent for many unhealthy conditions in the body.

Neprinol benefits:

  • Strong anti-oxidant effect
  • Helps clean the bowels and eliminates dead bacterial debris
  • Oxidises fatty acids
  • Lowers C-Reactive protein – an inflammatory marker
  • Helps promote maintenance of normal blood pressure promoting cardiovascular health
  • May be administered orally and is absorbed in the intestinal tract
  • Helps maintain normal blood viscosity
  • Anti-oxidant effects may be beneficial to promote normal prostate health
  • Promotes healthy muscle tissue and connective fibre
  • Boosts energy levels, increases alertness and concentration
  • Useful to promote leaness in body mass and aid protein utilization
  • Supplements the bodys natural enzyme reservoir
  • Activates naturally occurring plasmin
  • Thins mucous secreted by the mucous membranes
  • Attacks the Isoprin Bond on viruses helping to promote your bodys natural resistance
  • Potent fibrinolytic activity reduces systemic fibrin concentrations

Food allergies are partially digested proteins which are aborbed into the bloodstream. These proteins are known as CICs (circulating immune complexes). Once in the bloodstream the immune system treats them as invaders provoking an immune reaction. Over time too many CICs overwhelm the bodys ability to eliminate them so they are stored in the soft tissue where the immune system continues to attack them as allergens causing inflammation and ultimately auto-immune disorders.

Enzymes are proteins that catalyze (speed up) chemical reactions. Without enzymes, metabolism would be too slow to serve the needs of the cell. Metabolic enzymes regulate everything in the body from liver function to the immune system. Proteolytic enzymes also have the ability to digest and destroy the Isoprin Bond around viruses. This defence shield made up of proteins also surrounds bacteria, funghi and cancer cells.

Neprinol is safe to take with other nutritional supplements; i.e. vitamins, minerals etc. No serious or adverse side effects have been reported from taking systemic enzymes such as Neprinol AFD. Clinical studies have shown that even extremely large doses of these enzymes are not toxic. Most pharmaceutical drugs will not cause contradictory issues except for anti-coagulation medications such as Warfarin or Coumadin, which should only be combined with Neprinol AFD under the supervision of a doctor.


Neprinol & Serretia Testimonial Review:

Ive had this muscle pain in my lower arms for months which always surfaced during workouts, and after just a few days of taking Serretia and Neprinol its gone and hasnt come back.  I was blown away, so amazing.  If it can do that in a few days, just think what else it does, not to mention the stuff we cant see or feel.

M.E. Denmark.


Neprinol AFD Testimonial Review:

I have been using Neprinol since 6 months to fight Peyronies Disease and I experienced very good results.  Do you have patients struggling with the same problem?  I would appreciate if you could post their success stories on your website or send them to me.  Thank you.

B.L. (Hungary)


Neprinol AFD Testimonial Review:

First I must say thank you very much.  Because I feel very good after I start to take your supplement Neprinol.  Always I had a pain at joint of arm.  Sometimes have a backache.  But look at me now I cant believe I get a painless life again like in my youth!  Now I think I want to send this to my mom who living in Japan.  She is suffering from knee pain.  Can you send to Japan?

Tomoko Nakamura (U.K)


Neprinol AFD/Fibrovera/Serretia/Syntol/Vitacel 7 Testimonial Review:

I have been using Neprinol, Fibrovera, Seretia, GH7 (continuously) and Syntol (as needed) for about six months now.  I am a 51 year old woman, who has had the menopause and who has been used to being mentally and physically very active through out my life.

When I started using them I was feeling exhausted all the time, sluggish in my thinking, depressed about my lack of energy and having a  hard time sleeping at night.  The world felt decidedly grey.  I am a psychotherapist, and knew that these symptoms were not to do with anything going on in my life, but were more physically based.  Because of years of dancing and horse riding,  I also have arthritis in both hips and was looking for some relief from inflammation.

Initially (after taking these supplements) I went through a period of detoxing, feeling achy and still tired, but I could tell that my body was detoxing….. (many visits to the bathroom!) I also started immediately to feel more alive.  However within a few weeks I started to notice that my mind was becoming increasingly clear and that my energy was returning.

Now, though I am still aware that I am not 20….  (thank goodness)…… I feel positive, energised, clear thinking, and excited about life.  The world has regained its colour!  I have also found that I recover better from winter viruses and soft tissue injuries.

Sadly I have to say that I havent noticed much improvement in my arthritis, or my experience of inflammation, but to be fair, according to the x-rays that I have recently had done, the arthritis is advanced…. so that would be a bit of a miracle…!

I also found the support service that the company provides is excellent. I generally order by phone and receive very personal care and advice about dosage and a real interest in my on-going experiences using these supplements.

Honestly my quality of life is transformed.  The pills are expensive, but you can cut the dose down over time.  However I feel that it is more that worth it.

Ros S. Pembrokeshire.

Frequently Asked Questions

What is Neprinol?

Neprinol is a proprietary combination of Serrapeptase, Nattokinase, Protease, Lipase, Bromelain, Papain, Rutin, Amla and other proteolytic enzymes that are specially formulated to support healthy fibrin levels. Neprinol has been used to support immune and circulatory health, as well as maintain a healthy inflammatory response.*

What are Enzymes?

Enzymes are proteins (or protein-based molecules) that act as catalysts in biochemical reactions.  Every enzyme has a specific reactant known as a substrate, which can be thought of like a lock and a key.  Only a specific enzyme (or key) will react (or unlock) its substrate. This is the reason why enzymes are unable to break down necessary and vital tissue, as they only react with certain harmful proteins in the body.

What are "Systemic Enzymes"?

When enzymes are introduced into the bloodstream, they work “systemically”, or throughout the entire body.  Taking enzymes on an empty stomach allows them to work systemically since they will bypass the upper digestive process and enter the bloodstream through the intestine.  Systemic enzymes are similar to digestive enzymes, though certain enzymes are better designed for systemic activity as opposed to digestion due to the materials they react with, such as Serrapeptase and Nattokinase.  These two enzymes are very efficient with the breakdown of a particular substance known as Fibrin.

What is Fibrin?

Fibrin is a protein substance naturally formed in the human body that plays a significant role in our health and general well-being.  Fibrin is responsible for scar tissue formation, and is produced as a reaction to injury.  Our bodies naturally maintain healthy fibrin levels with enzymes (principally plasmin) whose role is to attack and break down any excessive fibrin. As fibrin builds up in the body, it can cause many unhealthy conditions.

Why Neprinol?

As we age, our natural enzyme production decreases while the need for these enzymes is of increasing importance. Supplementing these valuable enzymes can combat enzyme deficiencies that can lead to a wide variety of health concerns.  Healthy levels of these enzymes can assist the body in maintaining a healthy immune system, healthy joints, proper circulation and an overall balanced reaction to injury. 

How Does Neprinol Work?

By supplementing and replenishing the body's diminishing enzymes, Neprinol provides one of our most essential and basic biochemical needs.  It supplements the body's natural fibrinolytic enzyme levels thereby helping to maintain healthy fibrin levels: an underlying causative agent for many unhealthy conditions in the body

Is Neprinol Enteric Coated?

Enteric coatings are designed to protect enzymes and other supplements from stomach acid. Plastic-like chemicals known as phthalates are often used in this coating process. Phthalates are actually banned in children's toys in Europe and Mexico, so why would we ever include these in our formulas? Arthur Andrew Medical has instead developed an all-natural, chemical-free Acid Armor capsule. These capsules are comprised of an extra-thick layer of cellulose (vegetable capsules) with a micro threaded locking mechanism to prevent leaking. Acid Armor capsules have been designed to delay the release of the capsule's contents for up to an hour without the use of potentially harmful chemicals.

Is Neprinol Safe?

No serious or adverse side effects have been reported from taking systemic enzymes such as Neprinol*. If you are taking blood-thinning medication, you should consult with your physician before taking Neprinol.

Suggested use

When is the best time to take Neprinol?

For best results, take the product at least one hour prior to eating and/or two hours after a meal.

Can I take Neprinol with other supplements?

Neprinol can be used safely with other dietary supplements.

How long does it take for Neprinol to work?

Although every person is different, some have reported feeling the effects of systemic enzymes in as little as 45 minutes. For therapeutic regimens, the progression may be slow for some and quicker for others. Typically, supplementing the product for a minimum of a month's time is recommended, with the best results occurring anywhere from one to three months thereafter.

Directions: Take 1 to 4 capsules with 8 oz of water between meals or as directed by your healthcare practitioner. For therapeutic applications, take 3 or 4 capsules three times daily.

Warning: Do not take Neprinol without the consent of your physician if you are taking anti-coagulants or if you are pregnant or nursing.

Supplement Facts

Serratiopeptidase (Serrapeptase)

A proteolytic (protein digesting) enzyme with potent fibrinolytic activity which may support healthy fibrin concentrations.* It has been clinically shown to thin secretions from the mucus membranes, and also promotes normal recovery after physical stress, boosting energy levels.*


A fibrinolytic enzyme that can help to maintain normal blood viscosity and normal cardiovascular health.* Like Serrapeptase, Nattokinase can support healthy fibrin concentrations.* It has antioxidant effects that may be beneficial to promote normal prostate health, and aids in the elimination of free radicals.*


Used systemically, this enzyme digests fats in the blood and can help to convert fats into fatty acids which may be expressed or retained as (energy).*


A proteolytic enzyme that, when present in blood serum, plays an important role in blood clotting as well as lysis of clots.* May be beneficial to help support a healthy immune system.*


Derived from Indian Gooseberry, Amla contains tannic acid, glucose, cellulose, and calcium. Amla helps maintain normal acid and pH balance, and has the highest concentration of any naturally derived vitamin C.*


A proteolytic enzyme derived from papaya that can promote normal healing of bruises and other tissue injuries.*


A proteolytic enzyme derived from pineapple that acts with the body to promote its normal immune responses.* Bromelain can also help in the maintenance or normal healthy skin.*


A flavonoid (plant pigment) that helps to maintain strong capillaries and connective tissue, as well as healthy blood vessels.*

Coenzyme Q10

Decreases the proliferation of free radicals, supporting a healthy immune system. *Co-Q10 helps promote maintenance of normal cardiovascular function and is a coenzyme that is essential for enzymes to function in the body.*


Promotes a healthy cardiovascular system, and is essential for cell repair, hormones and a regular heartbeat.* Magnesium helps reduce effects of increased stress.*


Testimonial 1

OMG!!!!! I can not say it enough. A friend told me about these wonder pills to help reduce my keloid scarring. Not only are the scars melting away after just two weeks of use I have lost about 9lbs in the same amount of time. I suffer from Chronic Inflammation plus a few other things and my usual visible swelling (face, legs, feet, @ etc.) have noticeably diminished. The cost is high and might prove to be hard to allow most to maintain as needed but if you can it is well worth it. Wow!!!

Testimonial 2

I started taking Neprinol 2 weeks ago. Todays date... 6/20/2014, I feel the best I have ever felt. I have severe Rheumatoid Arthritis, and have had many years of heavy medications that are supposed to have healing abilities. With no avail, I was miserable everyday, with the hope of feeling better. This is the best thing I've ever happened upon. I wish the Rheumatologist would have prescribed this instead of the Gold Shots, Methrotrexate, Celebrex, and the other B.S. that gives you mood changes and diarrhea. This product has rid me of the constant call of PAIN everyday in just two weeks. I cant wait to see what is it does in a month.... even a year from now. I will post monthly on my success. I believe this is the solution for me. This product has won me over.

Testimonial 3

I started using this product in 2004 after having two operations for Fibroid removal. When I returned to my doctor for an annual check-up after the second operation, I was told that the Fibroids had returned. I didn't want a third operation so I looked on the website and this is one of the products that I discovered. I took it along with Vitalzym, DIM and Progesta Care cream and in 6 months, the Fibroids were gone.

It also worked for my cholesterol levels, blood pressure as well as my shoulder pain.

Testimonial 4

I am so glad I did my research before filling my prescription. My Dr. wanted me to start taking Coumadin to thin my blood. I wanted to try something natural first, so I started taking Neprinol. After 3 months of taking 3 capsules twice a day I lowered my total cholesterol from 319 down to 197. My Dr. was so impressed, he called the company that manufactures this product, Arthur Andrew Medical. He is now recommending this product to many of his patients. All I can say is WOW, and I also have more energy than I have ever had. I will continue to take this product, I can't wait for my next cholesterol test.

Testimonial 5

Of all the supplements I've tried this one is probably the best for chronic inflammation, pain, prevention of common colds/flus, etc. If I was stranded on an island and could only choose 1 supplement, this would be it.

The past 1-2 months, I've been eating all the wrong foods and usually my stomach will flare up badly. However, with even a small dose of 3 caps daily- no problems at all. This can't be coincidence since this is the only thing I've changed. Of course, it would be even more helpful if I ate the right foods :)

It has only been 2 months and I feel a difference. A dosage of 3 caps 2x a day would probably be better. For serious conditions, I would guess 3 caps 3x a day would be best per their website.

Keep in mind, no supplement is a cure all. If for a long time you eat crap, don't sleep, stress a lot and don't exercise, don't expect much. Even still, I've tested it under these conditions and it still works! :)

Testimonial 6

I surf the ocean around Maui and needed something for my knee. I was suffering from pain after a soccer injury to the cartilage. limited range of motion and the small obstruction was gone after taking Neprinol.

Testimonial 7

Both Neprinol AFF and Serretia improve Health and lung function. Doctors are amazed at how quickly and well my lungs are recovering from unexplained pulmonary disease. Each day I notice improvements in blood oxygen saturation levels and overall return to fitness. 

Testimonial 8

Started using this product after a second cardiac event after my initial myocardial infarction and the implant of four drug eludcating stents. Results have been FANTASTIC, I can actually feel the increased blood flow to my heart and my anxiety, about my overall health has exponentially lessened. Thanks for putting out an outstanding product that I'm sure has helped save many lives.


Testimonial 9

Love Neprinol been using it to remove cysts from my ovaries and thyroid gland. I have used it for approximately 9 months. Would like to continue to use it but have had to cut my dose back because its a bit pricey. Guess you can put a price on good health though huh!

Testimonial 10

Excellent Product! My body started to feel so much better after 3 days of use! Highly recommended!

Testimonial 11

I started taking this for scar tissue and inflammation for back and knee problems. I had also had been diagnosed with purpura, (excessive bleeding under the skin), I was told this is just old skin, nothing could be done, etc. The purpura was gone within three weeks of starting Neprinol AFD. This week I had Flu like symptoms, and took about 10 capsules. The next day I felt great. I have used alternative medicine for years, but I do want to read clinical evidence to back it up. I've been a nurse for 35 years, and never seen results that compares to this.

Testimonial 12

I have used Neprinol for years. There is almost nothing that it won't help. I have bad knees and Neprinol really has functioned as an anti-inflammatory for my knees. There have been times when it has helped with blood pressure. It has helped with pain. It has helped with sinuses. It is a cutting edge product made to the highest standards (though I wished they would switch to ubiquinol COQ10). That aside I can't say enough good things about Neprinol which we have used for years. The product claims to help regulate fibrinogen--the viscosity of the blood which impacts on heart attack and stroke. My husband takes it daily preventively as their is a history of stroke in his family. We believe it to be a functional product with fewer side effects than aspirin for this purpose.

Testimonial 13

12 capsules a day is noticeably improving knee tendonitis and a pulled bicep. To increase dose gradually because too much too soon can cause diarrhea.) I have taken this product before for inflammation and it worked very well. I also notice a pleasant feeling of looser joints and muscles as well as a mild feeling of increased well-being when taking 4 capsules a day maintenance dose. This is one of the best supplements I've discovered in 25 years. For sports injuries, Serretia (serrapeptase) was even more effective for me.

Testimonial 14

Neprinol AFD has made a huge difference for us. We feel more energetic over all; digestion has improved also.

Owen Founder of Higher Self Herbs:

I LOOOOVE Neprinol !!! AMAZING enzyme formula we're BLESSED to have. This and Serretia have helped my sinuses and breathing, SLEEP (waking up super refreshed and fast and needing less sleep), having more ENERGY and overall cleansing, decongesting of mucus and helping my body to heal from 13 years worth of ill health. This alongside many other herbs and a medium-high% raw food diet, I'm catapulting back into LIFE again with an abundance of well being, energy and constantly increasing my fitness and happiness in life. Hope you enjoy this formula as much as I have! Peace, love, light and appreciation - Owen